Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration

Decellularized Swine Dental Pulp as a Bioscaffold for Pulp Regeneration

Endodontic regeneration shows promise in treating dental pulp diseases; however, no suitable scaffolds exist for pulp regeneration. Acellular natural extracellular matrix (ECM) is a favorable scaffold for tissue regeneration since the anatomical structure and ECM of the natural tissues or organs are well-preserved. Xenogeneic ECM is superior to autologous or allogeneic ECM in tissue engineering...

Pulp Regeneration by Harnessing Dental Pulp Stem Cells

Tissue Engineering Considerations in Dental Pulp Regeneration

Regenerative endodontic procedure is introduced as a biologically based treatment for immature teeth with pulp necrosis. Successful clinical and radiographic outcomes following regenerative procedures have been reported in landmark case reports. Retrospective studies have shown that this conservative treatment allows for continued root development and increases success and survival rate of the ...

Regeneration of Dental Pulp- A Review

The regenerative potential of dental pulp is very limited in mature teeth. However, our improved understanding of pulpal inflammation and repair and improved dental materials and technologies make vital pulp therapy a viable alternative to root canal treatment. This article explores our knowledge in this regard and the future potential of saving or even regenerating the pulp as a routine dental

Extracellular matrix of dental pulp stem cells: applications in pulp tissue engineering using somatic MSCs

Dental Caries affects approximately 90% of the world's population. At present, the clinical treatment for dental caries is root canal therapy. This treatment results in loss of tooth sensitivity and vitality. Tissue engineering can potentially solve this problem by enabling regeneration of a functional pulp tissue. Dental pulp stem cells (DPSCs) have been shown to be an excellent source for pul...